Category Archives: blog

Vitamin-D and Prostate Cancer

Vitamin-D and Prostate Cancer

2014-11-19

A new study out of the University of Colorado Cancer Center in Denver finds that vitamin-D and prostate cancer are inexorably linked. The essential nutrient regulates the gene GDF-15. But in cases of prostate cancer driven by inflammation, when vitamin-D is absent so is the gene. The peer-reviewed journal Prostate published the study. Lead author James R. Lambert, PhD. said, “When you take vitamin D and put it on prostate cancer cells, it inhibits their growth. But it hasn’t been proven as an anti-cancer agent. We wanted to understand what genes vitamin-D is turning on or off in prostate cancer to offer new targets.” The group proved that vitamin-D regulates the gene, and wanted to further prove that this particular gene was how vitamin-D affected prostate cancer. Dr. Lambert wrote in the press release, “We thought there might be high levels of GDF-15 in normal tissue and low levels in prostate cancer, but we found that in a large cohort of human prostate tissue samples, expression of GDF-15 did not track with either normal or cancerous prostate tissue.” But then they noticed something else.

Sunshine Vitamin D

The presence of GDF-15 was low in human prostate cancer tissue samples where inflammation was present. Dr. Lambert said, “Inflammation is thought to drive many cancers, including prostate, gastric, and colon. Therefore, GDF-15 may be a good thing in keeping prostate tissue healthy; it suppresses inflammation, which is a bad actor potentially driving prostate cancer.” Researchers utilized a sophisticated new technique in this study, using computer algorithms to analyze biochemical data. Gene GDF-15 was shown to inhibit NFkB, a biochemical compound which was shown to contribute to cancer growth and inflammation in previous studies. Dr. Lambert said, “There’s been a lot of work on inhibiting NFkB.” He added, “Now from this starting point of vitamin D in prostate cancer, we’ve come a long way toward understanding how we might use GDF-15 to target NFkB, which may have implications in cancer types far beyond prostate.”

Performance Anxiety when Trying to Conceive

Performance Anxiety when Trying to Conceive

2014-11-12

When you first start trying to have a baby, it can seem too good to be true. There are no more condoms to fool around with. Your partner may be extra motivated, which is always fun. Certain days you know, no matter what happened that day, you are getting lucky that night. But after some time, say months or even a year, what was once an added bonus can turn into a liability. Los Angeles marriage and family therapist Aaron Buckwalter says, “…after 6 months of no pregnancy, people start to get a little worried. Part of this worry derives from hearing so much about infertility that people start to get anxious and move rapidly into concern about infertility.” This is where sex turns a corner. Instead of fun, it becomes a chore. Buckwalter says, “Some books and doctors recommend having sex twice a day during the ovulation period. Having sex 6 times in three days sounds like it could be fun, but can lead to performance anxiety and often anger and resentment.” This negativity is carried into the bedroom. But how men and women deal with such emotions is different.anxiety (1)

“Men do typically bear the brunt of performance anxiety as couples try to conceive,” Buckwalter says. “When the pressure is on to have sex numerous times in a short time period, many men have erection difficulties and also difficulty achieving orgasm each time. If there is a ‘failure’ in one of those attempts, it can compound the pressure later in the day or the following day to perform their duty successfully.” The woman’s own anxieties can compound the issue. With so much pressure and negative emotions building up on both sides, and the spontaneity and playfulness gone out of it, it’s no wonder so many guys have performance anxiety at this crucial time. So how can you overcome it? According to Buckwalter, “Rather than giving into the timetable and feeling rushed, the couple should relax and try to re-introduce playfulness into the situation. It can be a good time to check in with each other about fantasies or role playing ideas and other ways to distract them from the timetable.” Make it more like in the old days. Don’t feel pressured. Instead, find ways to deal with your anxiety. Talk about it and see how she feels, too. Once you clear the air and deal with those negative emotions, lovemaking can become organic and exciting, and less of a chore. If performance anxiety still exists, seek out a counselor or sex therapist. If you cannot conceive after one year of trying, see a fertility specialist.

The Not-So-Incredible Shrinking Penis

The Not-So-Incredible Shrinking Penis

The size of a man’s member means a lot in our society. Most men know about shrinkage. Whether or not women do is another matter. That famous episode of George Canstanza being walked in on, on “Seinfeld” comes to mind. Most men know that cold water temporarily causes shrinkage. This is because the cold forces the penis to move closer inside the body, in order to remain warm. Of course, this state causes no permanent damage whatsoever. There are other causes however, which can also affect both length and width. Some are temporary. Taking care of your member and your health can help you avoid it. One place not to worry about this phenomenon is when working out. During exercise, blood rushes to the muscles to give them oxygen and nutrients. When this happens, other areas become smaller. That doesn’t mean any damage is dealt. In fact, exercise overall is one of the healthiest things you can do.shrinkage

Being overweight may make the penis look smaller. But the extra fat around the pubic area doesn’t actually shrink the organ. It just hides it, somewhat. In fact, losing weight will make it look bigger. These have been temporary issues so far. Instead, long-term shrinkage is actually penis atrophy, and that spells trouble. The tissue of the penis reduces due to a serious health issue. One such thing that can cause it is smoking. Not only does ingesting tobacco hurt performance, and cause ED, it can also create visible shrinkage in girth and length. This is because toxins in tobacco hurt nerves, muscles, and blood vessels in the penis, and elsewhere in the body. Quitting may restore lost size. Penis tissue needs a constant supply of blood to bring it oxygen and nutrients. Poor circulation can limit these things, causing there to be less tissue in the most important of areas. Eating healthier and exercising can help improve circulation. A low level of testosterone limits the amount of erections a man has. Without a periodic rush of blood to the area, the tissue atrophies. Peyronie’s disease, usually an arc to the penis due to a buildup of scar tissue, can cause the inability to have sex, pain, and shrinkage. If you have this, see a doctor right away. Lastly, simple aging shrinks many areas of the body. The penis is sometimes one of them. Keep up a healthy lifestyle and you will maintain sexual and overall health. And the next time you change after swimming, make sure the door is locked.

Are any Penile Enhancement Products Effective?

Are any Penile Enhancement Products Effective?

2014-11-06

“Penis enhancement” products are all over the internet. Put that phrase into Google and some 4.28 million search results come up. The most common methods include pumps, drinks, and pills that claim to elongate and widen the male member. Most are illegitimate. But are any of these products effective? According to the director of the University of Washington’s Men’s Health Center, Thomas J. Walsh, M.D., “To date there’s never been a cream, a pill, or anything of that nature that’s been shown to benefit phallus size.” He added, “There’s no quick, one-shot way to increase the size or the function of the male penis.” There are pills that can engorge the penis with blood faster, but that won’t increase size. The good news is, most men who think they are small aren’t, at least according to Larry Lipshultz, M.D. He is the chief of male reproductive medicine and surgery at Baylor College. Lipshultz says, “The majority of men who come in seeking penile enlargement are average.”enhanced

Marketers of such products pray on men’s feelings of inadequacy to make sales. Lipshultz says, “I just don’t think men have a realistic idea of what normal is. Hence they think that they are below normal when actually they’re average.” According to research published by the Journal of Sexual Medicine the average size is just 5.6 inches, which it turns out is plenty to satisfy a woman. One way to make it seem larger is to lose weight. Look at the area and notice if you have “suprapubic fat.” This can make the penis appear smaller. If it is in fact getting smaller, this is a sign of a serious medical issue. Difficulty creating or maintaining an erection is an issue to address with a physician or urologist. Dr. Walsh says, “There’s a very strong association between new erectile dysfunction and subsequently experiencing a cardiovascular event.” If you really want to be a superstar in the bedroom, avoid enhancement products. Instead, follow Dr. Walsh’s advice, “Improving your overall physique, reducing body fat, increasing lean muscle, and improving cardiovascular health have all been shown to enhance sexual performance.” The takeaway, “Anything you could think of to improve your overall health outlook is going to improve your sexual function and your sexual appearance,” Walsh said.

Low Testosterone and Type-2 Diabetes tied to Higher Vascular Risk

Low Testosterone and Type-2 Diabetes tied to Higher Vascular Risk

Doctors have long seen a connection between type-2 diabetes, vascular problems and erectile dysfunction. But this is the first study to connect the other two with low levels of the male hormone. This was a cross-sectional study. All participants had type-2 diabetes, low serum testosterone levels—the kind that freely roams the bloodstream, and had a greater risk of thickening of the carotid artery. This is the one leading to the brain. Blood clots in this blood vessel can cause a stroke. These participants had six times greater risk of what is known as carotid artery intima media thickness (CIMT). 31% of the participants had low testosterone which was linked to a higher risk of vascular disease, known in medical terminology as atherosclerosis. The study was conducted by the Hospital Universitario Sanatorio Guemes in Buenos Aires, Argentina, in conjunction with Emory University in the U.S. The results were published online in the peer-reviewed Journal of Clinical Endocrinology & Metabolism.Doctor-examining-patient-obese

Dr. Javier Mauricio Farias was the lead author of the study. Emory’s Dr. Guillermo E. Umpierrez co-authored. Umppierrez said in a statement, “Several cross-sectional studies have reported that about one-third of adult patients with obesity and type 2 diabetes have low serum testosterone.” He added, “Our study indicates a strong association between cardiovascular disease and low testosterone but does not prove causation.” The authors note that few studies have looked at a link between low testosterone, atherosclerosis and type-2 diabetes, before. Doctors say that the choice to administer testosterone replacement therapy, in hopes of saving men with these combined conditions, is controversial and up to their physician’s discretion. The researchers wrote, “Prospective randomized studies are needed to assess the clinical significance of our findings and the clinical impact of testosterone replacement on cardiovascular risk factors in diabetic patients with low total testosterone.” The role of testosterone replacement therapy (TRT) was not included in this study. However Dr. Umpierrez noted, “In elderly patients with evidence of atherosclerosis, testosterone replacement has not been shown to be of benefit and may even increase the risk of cardiovascular events.”

DOES ROMANCE KILL MEN’S SEX DRIVE?

DOES ROMANCE KILL MEN’S SEX DRIVE?

2014-11-02

Romance primes her body for the bedroom. But for men, it may have the opposite effect. (Dylan & Sara/Stocksy)

Turns out, there may be a scientific reason why movies based on Nicholas Sparks novels are called “chick flicks.” Watching romantic movies revs women’s sex drives — but it also dampens men’s desire to hit the sheets, according to a new study in the journal Archives of Sexual Behavior.

In the world of sex research, there’s a theory about sexual desire called the “incentive motivation model.” That’s a technical way of saying arousal starts with a rewarding stimuli (for example, seeing your partner naked), which automatically leads to a boost in below-the-belt blood flow. Once you realize your body is responding, your mind joins the arousal process, which only heightens your physical response, compelling you to seek sex.

As simple as that sounds, the first step — the sexual stimuli that kicks off the whole arousal process — can vary dramatically between men and women. Take porn, for example. “In a lot of research, when women watch porn movies, their body reacts — they’re genitally aroused — but they don’t feel anything,” lead study author Marieke Dewitte, an assistant professor of clinical psychological science at Maastricht University, told Yahoo Health. However, “we know that if you let women watch porn that is more female-oriented, embedded in a story, they respond with more sexual arousal.”

This suggests that, for women, it’s not just what the sexual stimuli is that matters, but also the context in which they encounter it. “Their sexuality is more dependent on the relationship context,” Dewitte explained.

That’s what inspired the design of her study: 86 men and 78 women watched three video clips — shots of a couple having sex; the scene from Titanic when Leonardo DiCaprio and Kate Winslet share their first smooch, along with a romantic clip from Indecent Proposal; and snippets of a documentary about English history. After watching each clip, the study participants rated how turned on they felt, both mentally and physically. They also completed a survey that measured how much they wanted and liked sex.

Women reported a greater desire for sex after watching theTitanic and Indecent Proposal clips, compared to the sex scenes. Men, on the other hand, were most inclined to do the deed after watching the explicit clips. And, surprisingly, they felt more desire after seeing the boring English documentary than after watching the romantic movies.

romancing

What’s going on? Simple: Women may use romantic scenes as a jumping-off point to conjure their own sexual fantasies — say, imagining being seduced by someone like Jack Dawson in Titanic. By contrast, “men need more visual information,” said Dewitte. As a result, guys tend to favor explicit sexual stimuli (like pornography), possibly because they’re wired to reproduce with lots of partners, rather than nurturing a romantic bond with one woman. “For women, the attachment system is more important, so the partner stays with them and raises the child,” she said. “So it makes sense that sexuality is much more related to the relationship.”

We’ve all heard the “men are more visual” spiel before. But, more importantly, this study helps debunk the long-held theory that men are simply more sexual than women. Dewitte found that in a test designed to measure “implicit” feelings — that is, automatic responses, rather than thought-out replies — women liked sex just as much as men. “If you put women in the right context, they experience as much — or even more — sexual desire than men,” she said. “They don’t always like sex the way men like it. They like kissing, they like intimacy.”

So how can couples overcome this mismatch in cues for sexual desire?

Men: Invest in the relationship

You’ve heard it before: Foreplay starts outside the bedroom — and we don’t necessarily mean fooling around on the couch. “Invest in the relationship during the day,” Dewitte said, which can including sending a lovely message, bringing her a gift or telling her she’s beautiful. These little acts of romance help kick her arousal system into high gear: When a woman senses her partner is emotionally invested, she’s more likely to be primed for fun in the bedroom later. “Men, if you want to have sex with your partner, don’t wait until you’re in the bedroom, and then quickly caress her,” she said.

Women: Pay attention to your body

Learn to listen to your body: Can you feel your heart beating faster? Your arousal building? Make sure to do the same for your partner, too — if you try to detect when he’s aroused, you might just find your own body responding.

Women: Figure out what excites you

As a sex therapist, Dewitte often asks her female patients this question: In order to become sexually aroused, what do you need? “A lot of women don’t know what they need,” she said. “So I ask them to go on the Internet, read books, learn for yourself, ‘What turns me on?’” In her experience, erotic stories often do the trick for women since, unlike porn, naughty reading material allows them to conjure up their own visuals. “Men have to watch — they have to see a breast or an explicit visual cue,” she said. “For women, it’s much more about fantasy.”

Women: Take time to fantasize

If you feel awkward fantasizing, that’s totally normal — it actually can take practice. “Sometimes, in the beginning, it’s not spontaneous at all,” Dewitte said. Her advice: Set aside five minutes a day, and try to script your own sexual fantasies in your head. You may find it tough at first, but eventually you’ll get the hang of it. “You can learn to fantasize,” she said.

What really Causes Performance Anxiety?

What really Causes Performance Anxiety?

2014-10-28

It may feel like you are the only one. But there are millions of men of all different ages, relationship statuses, and sexual orientations that struggle with performance anxiety. Usually it occurs when a man pictures a negative outcome as a result of taking part in a sexual act. He soon becomes preoccupied with his anxiety. This triggers the fight-or-flight response which then disengages the body from the sexual mode, generally deflating his erection, and making him unable to engage in intercourse. For some, it is a vague fear that can occasionally stifle a man’s performance. For many however, the trouble is deeply rooted in general feelings of insecurity or inadequacy. But for many sufferers, these feelings have never been spoken about. Fear of being rejected by a partner, of being unable to satisfy, or being humiliated in the bedroom are the forms the anxiety takes.anxiety

Erectile dysfunction drugs like Viagra, LeVitra, and Cialis are effective for some men. They make having an erection a lot easier, and focus is then turned to pleasing his lover. But for others, where these feelings are deeply rooted, anxiety can still degrade or inhibit performance. Though many men experience anxiety from time to time, one instance of performance difficulty will often reinforce negative feelings, making performance that much harder the next time, creating a vicious cycle. For those with deep seeded performance anxiety, it is important first to get checked out by a urologist to make sure no physical issues are at fault. Once physiology is ruled out, psychology becomes the concern. Seeing a psychologist or a sex therapist can help. One technique therapists employ is called sensate focus. This is positioning the couple where all focus on erection and intercourse is removed. Instead, the attention is placed on arousal, fun, pleasure, and the emotional state both partners inhabit when enjoying physical play. Couples engage in touching, long bouts of foreplay, and oral and digital stimulation without any mention or regard to insertion. The couple focuses on enjoying their time together. Generally speaking, when all pressure is removed, the man’s confidence can be built up. Once that occurs, the ability to perform returns and anxiety is eliminated.

A very Attractive Partner can Cause Performance Anxiety

A very Attractive Partner can Cause Performance Anxiety

Most guys want an attractive partner. Not only are they amazing to look at and experience, but they also give his social status a boost. Trouble is no guy ever considers the drawbacks to being with such a person.  So what’s the downside? A very attractive partner, or one that appears perfect in your eyes, can lead to performance anxiety, even cause erectile dysfunction. Men often feel pressure to perform well in bed. Seeing one’s partner as too attractive or too perfect increases that pressure. If the man feels too much anxiety, he will feel that no matter what he does, he cannot measure up. So here sex, instead of becoming a joyous prospect, is riddled with feelings of anxiety, inadequacy, and fear. Not only can this hurt the man’s sex life, it can hurt his relationship too. The partner may feel as though they are being rejected. Even very attractive people have anxieties about their looks, body image issues and what have you. This may exacerbate them, pulling you two apart.

sexual-performance-anxiety

This phenomenon can occur for men of all ages. Of course, if there is no biological issue, than the psychological one needs to be addressed. Men experiencing erectile dysfunction should however get checked out by a physician or urologist, just to make sure that everything is indeed alright. The next step is to build confidence. Talk to your partner about how you feel. They may think you aren’t interested in them anymore, when the exact opposite is true. When the time comes, go slowly. Ask your partner to give you positive reinforcement, such as compliments or encouraging, sexy phrases to reinforce positive feelings and dispel negative ones. Do not retreat into your head. This is where the negative thoughts stem from. Instead, practice being totally focused on the present moment with your partner. Consider all of your senses. What does their skin taste like? What does their hair smell like? Giving compliments can help warm them up too. Spend lots of time on foreplay. Include digital or oral play. Most women need clitoral stimulation to orgasm anyway, something that usually doesn’t occur during intercourse. It’s hard not to feel confident with a moaning or satisfied partner next to you. If none of these help, be sure to seek out a qualified, mental health professional, or a sex therapist.

Penis Transplants may soon be a Reality

Penis Transplants may soon be a Reality

2014-10-20

A penis grown in a lab may sound like something out of a weird movie, created by some deranged mad scientist, but in fact it may be reality soon. Two trials to cultivate the male member in a lab are in the works, the price tag taken care of by the Armed Forces Institute of Regenerative Medicine. The studies are being conducted by Wake Forest Institute for Regenerative Medicine. Their spokesperson Karen Richardson told the Huffington Post via email, “The goal is to conduct a clinical trial within the next four to five years.” In 2009 the institute created a “functional engineered solid organ.” This was penile erectile tissue for rabbits. But now they are ready to construct a human penis. The results, if successful, could help men who have lost their member to an injury, cancer, who have intractable erectile dysfunction, or even congenital defects. Lead researcher and director of the institute Dr. Anthony Atala said that a donated organ is pivotal to this research. It must then be broken down to its basic structure.

Researchers use it like scaffolding. Cells are grown on top of the structure. Once the organ is fully grown, it can be attached to the man who requires it.  Dr. James Yoo is also working on this project. He told The Guardian, “Think of it like a building. If you remove all the furniture and the people, you’re still left with the main structure of the building. Then you replace the tenants with new ones. That’s the whole idea. It’s just that the building is a penis and the tenants are cells.” Researchers note that this won’t work for transgender men who generally select confirmation surgery as “this method requires the use of the patient’s own penile cells.” Though it could feel like something out of a science fiction movie, in another series of experiments, scientists have attached four lab-created vaginas to women. One wonders whether in the far off future, if these penile researchers are successful, if men will be able to have larger organs surgically attached to replace their original equipment, and what impact this may have on society.

Childhood mental health disabilities on the rise

Childhood mental health disabilities on the rise

2014-10-16

Over the past half century, the prevalence of childhood disabilities in the United States has been on the rise, possibly due to an increased awareness about these issues. Now a study published in this week’s online issue of Pediatrics suggests the nature of those newly diagnosed disabilities is changing.

The report, “Changing Trends of Childhood Disability, 2001-2011” found the number of American children with disabilities rose 16% over a 10-year period. While there was a noted decline in physical problems, there was a large increase in disabilities classified as neurodevelopmental conditions or mental health issues, such as ADHD and autism.

“We found that that physical disability health conditions in children were down 12%, but the disabilities related to mental and neurodevelopmental health went up 21%,” said lead study author Dr. Amy Houtrow, chief of the Division of Pediatric Rehabilitation Medicine at Children’s Hospital of Pittsburgh.

Researchers looked at data collected from the well-known National Health Interview Survey between 2001-2002 and 2010-2011. In the survey, parents were asked to fill out a questionnaire indicating if their children had any health disadvantages such as speech and language disabilities, ADHD, intellectual disabilities, and/or emotional and behavior problems.

They found, not surprisingly, that children from poorer families still had the highest rates of disabilities overall. But they also found that children living in more affluent homes reported the largest increase in disabilities: 28.4% over the study period.

“The disparities were interesting and not really expected,” said Houtrow. “But the steepness in the rise (of disabilities in affluent children) makes me think there has to be different stresses, environmental experiences and or other risk factors in these families. All this needs to be studied.”

Houtrow said the changes could be due to a number of things. For instance, people in higher economic groups are often more comfortable dealing with children’s disabilities, both mental and physical, she said, so they’re more likely to seek help from their doctor. This could lead to more accurate reporting from that income bracket.

“Poorer families have other things to worry about first, including putting food on the table,” Houtrow said. “Their children’s learning disabilities are of concern, but they need to deal with other things, like hunger, lack of good health care and other factors.”

This is certainly not the first study to see an upward trend in mental health disabilities in children in recent years. The Centers for Disease Control and Prevention released a study in 2008 that saw a significant jump in ADHD and learning disabilities. And earlier this year, the CDC released another report saying 1 in 68 children in the United States has an autism spectrum disorder, a 30% increase from 1 in 88 two years ago.

child-with-puzzle-story-top

Houtrow hopes the study’s findings will open up further investigation into why these trends are happening. The authors concluded that documenting these changes in childhood disabilities is a positive step in developing better prevention methods, and treatments and services for these children.

“I think it’s a call to action,” said Houtrow. “It’s a call to action to the health care system and a call for additional research. And it’s a call to action to parents to be concerned about their child’s development. … Healthy children grow up to be healthy adults. Knowing how to better treat our younger generation is important to this country’s future.”